Compensatory mechanisms for chronic cerebral hypoperfusion in patients with carotid occlusion
Compensatory mechanisms for chronic cerebral hypoperfusion in patients with carotid occlusion
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DOI：
10.1161/01.str.30.5.1019
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发表时间：
1999-05-01
期刊：
影响因子：
8.3
通讯作者：
Powers, WJ
中科院分区：
文献类型：
--
作者：
Derdeyn, CP;Videen, TO;Powers, WJ
Background and Purpose-The purpose of this experiment was to assess long-term cerebral hemodynamic and metabolic changes in patients with increased oxygen extraction fraction (OEF) in the hemisphere distal to an occluded carotid artery who remain free of stroke.Methods-Ten patients with increased OEF and no interval stroke underwent repeated positron emission tomography examinations 12 to 59 months after the initial examination. Quantitative regional measurements of cerebral blood flow, cerebral blood volume, cerebral rate of oxygen metabolism (CMRO2), and OEF were obtained. Regional measurements of the cerebral rate of glucose metabolism (CMRGlc) were made on follow-up in 5 patients. Statistical significance (P
