Assessment of technical and biological parameters of volumetric quantitative computed tomography of the foot: a phantom study.
Assessment of technical and biological parameters of volumetric quantitative computed tomography of the foot: a phantom study.
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DOI：
10.1007/s00198-011-1851-3
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发表时间：
2012-07
影响因子：
4
通讯作者：
Prior, F. W.
中科院分区：
文献类型：
--
作者：
Smith, K. E.;Whiting, B. R.;Reiker, G. G.;Commean, P. K.;Sinacore, D. R.;Prior, F. W.
关键词：
很少有研究存在的骨密度测定的整个脚。一项体模研究证明了足部精确定量计算机断层扫描的误差来源和必要控制。小脚骨中骨矿物质密度的损失可能是糖尿病足并发症的早期指标。容积定量计算机断层扫描（vQCT）有助于评估足骨骨量减少，在周围神经病变的存在下，这可能是糖尿病足畸形的早期体征。迄今为止，尚未报告足部vQCT测量的误差来源和幅度。使用64层CT扫描仪扫描足模型。能量（kVp）、扫描床高度、体模尺寸和方向、“骨”插入物的位置、插入物材料、校准体模的位置和重建内核在扫描采集期间系统地变化。与在等中心点进行的基线120 kVp扫描相比，能量（kVp）和距等中心点的距离（检查床高度）导致相对衰减分别从−5%变化至22%和−5%变化至0%，平均骨矿物质密度（BMD）分别从−0.9%变化至0.0%和−1.1%变化至0.3%。与制造商规定值相比，BMD的平均范围为-2.2%至0.9%。与中等尺寸体模相比，体模尺寸和骨等效材料插入物的位置导致相对衰减变化为-1.2%至1.4%。本研究表明，kVp和扫描床高度的变化可以使用与足部体模相同能量和高度扫描的校准体模进行控制;但是，由于足部内软组织厚度和骨骼位置引起的误差无法单独使用校准体模进行控制。
Few studies exist for bone densitometry of the whole foot. A phantom study demonstrated the sources of error and necessary controls for accurate quantitative computed tomography of the foot. A loss in bone mineral density in the small foot bones may be an early indicator of diabetic foot complications. Volumetric quantitative computed tomography (vQCT) facilitates assessment of pedal bone osteopenia, which in the presence of peripheral neuropathy may well be an early sign of diabetic foot deformity. To date, sources and magnitudes of error in foot vQCT measurements have not been reported. Foot phantoms were scanned using a 64-slice CT scanner. Energy (kVp), table height, phantom size and orientation, location of “bone” inserts, insert material, location of calibration phantom, and reconstruction kernel were systematically varied during scan acquisition. Energy (kVp) and distance from the isocenter (table height) resulted in relative attenuation changes from −5% to 22% and −5% to 0%, respectively, and average bone mineral density (BMD) changes from −0.9% to 0.0% and −1.1% to 0.3%, respectively, compared to a baseline 120 kVp scan performed at the isocenter. BMD compared to manufacturer specified values ranged on average from −2.2% to 0.9%. Phantom size and location of bone-equivalent material inserts resulted in relative attenuation changes of −1.2% to 1.4% compared to the medium sized phantom. This study demonstrated that variations in kVp and table height can be controlled using a calibration phantom scanned at the same energy and height as a foot phantom; however, error due to soft tissue thickness and location of bones within a foot cannot be controlled using a calibration phantom alone.
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影响因子：
4.8
作者：
Bligh, Michael;Bidaut, Luc;Cody, Dianna D.
通讯作者：
Cody, Dianna D.
影响因子：
2.7
作者：
Schon, LC;Weinfeld, SB;Resch, S
通讯作者：
Resch, S
影响因子：
0.6
作者：
Chantelau, Ernst;Kimmerle, Renate;Poll, Ludger W
通讯作者：
Poll, Ludger W
影响因子：
1.3
作者：
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通讯作者：
GENANT, HK
影响因子：
3.8
作者：
Hangartner, Thomas N.;Short, David F.
通讯作者：
Short, David F.