Is the use of ultrasound-derived prediction equations for adults useful for estimating total and regional skeletal muscle mass in Japanese children
Is the use of ultrasound-derived prediction equations for adults useful for estimating total and regional skeletal muscle mass in Japanese children
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使用成人超声推导的预测方程是否有助于估计日本儿童的总和局部骨骼肌质量
DOI：
10.1017/s000711450899440x
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发表时间：
2009
期刊：
影响因子：
--
通讯作者：
Abe T.
中科院分区：
文献类型：
--
作者：
Midorikawa T;Sanada K;Yoshitomi A;Abe T.
本研究的目的是探讨超声导出的预测公式是否适用于青春期前的儿童和青少年，用于估计成人的总和区域骨骼肌（SM）质量。10名日本青春期前儿童和21名青少年自愿参加了这项研究。作为参考数据，从第一颈椎到踝关节获得1 cm厚的连续MRI图像。SM体积由数字化横截面积的总和计算。区域SM体积由扫描图像中可见的解剖标志决定。通过假设SM密度（1·041 g/cm3）将体积单位转换为质量。采用b超测量不同肌肉（前臂外侧、上臂前后、腹部、肩胛下、大腿前后、小腿前后）9个部位的肌肉厚度。利用成人预测方程估计SM总质量和区域质量。青少年SM总质量和区域质量测量值与预测值的平均值差异不显著，但青春期前儿童SM质量测量值与预测值的平均值差异不显著。在青春期前儿童和青少年中，95%的一致性范围相对较大。这些结果表明，成人超声衍生的预测方程在群体水平上可用于估计青少年的SM总质量和区域质量，但相对较高的变异性表明在个体水平上对青春期前儿童和青少年的可靠性有限。
The purpose of the present study was to investigate whether ultrasound-derived prediction equations for estimating total and regional skeletal muscle (SM) mass in adults are applicable for prepubertal children and adolescents. Ten Japanese prepubertal children and twenty-one adolescents volunteered for the study. Contiguous MRI images with a 1 cm slice thickness were obtained from the first cervical vertebra to the ankle joints as reference data. The SM volume was calculated from the summation of digitised cross-sectional areas. The regional SM volume was determined by anatomical landmarks visible in the scanned images. The volume units were converted into mass by an assumed SM density (1·041 g/cm3). Muscle thickness was measured by B-mode ultrasound at nine sites on different muscles (lateral forearm, anterior and posterior upper arm, abdomen, subscapular, anterior and posterior thigh, anterior and posterior lower leg). Total and regional SM mass was estimated using adult prediction equations. Mean values between measured and predicted total and regional segments of SM mass were not significantly different for adolescents, but were for prepubertal children. There was a relatively large range of the 95 % limits of agreement both in prepubertal children and adolescents. These results suggest that the adult ultrasound-derived prediction equations are useful for estimating total and regional SM mass for adolescents at the group level, but the relatively high degree of variability suggested limited reliability at the individual level both in prepubertal children and adolescents.