Three-dimensional and high-speed swept-source optical coherence tomography for in vivo investigation of human anterior eye segments
Three-dimensional and high-speed swept-source optical coherence tomography for in vivo investigation of human anterior eye segments
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DOI：
10.1364/opex.13.010652
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发表时间：
2005-12-22
期刊：
影响因子：
3.8
通讯作者：
Yatagai, T
中科院分区：
文献类型：
--
作者：
Yasuno, Y;Madjarova, VD;Yatagai, T
演示了二维和三维扫频源光学相干断层扫描 (SS-OCT) 系统，该系统使用可立即发货的扫描光源。该光源中心波长为1.31μm，-3dB波长范围为110nm，扫描速率为20KHz，频率扫描线性度高。本文提出了一种使用条纹分析技术进行光谱重新缩放的简单校准方法。该SS-OCT系统能够实时显示二维OCT，并且可以在测量时间为2 s的情况下获得三维OCT。在体内对人类眼前节进行二维和三维研究。经实验确定系统灵敏度为112 dB。三维 OCT 体积揭示了眼前节的结构，这在二维 OCT 图像中很难观察到。二维断层摄影电影显示了人类虹膜的动态运动。 (c) 2005 年美国光学学会。
A two- and three-dimensional swept source optical coherence tomography (SS-OCT) system, which uses a ready-to-ship scanning light source, is demonstrated. The light source has a center wavelength of 1.31 mu m, -3 dB wavelength range of 110 nm, scanning rate of 20 KHz, and high linearity in frequency scanning. This paper presents a simple calibration method using a fringe analysis technique for spectral rescaling. This SS-OCT system is capable of realtime display of two-dimensional OCT and can obtain three-dimensional OCT with a measurement time of 2 s. In vivo human anterior eye segments are investigated two- and three-dimensionally. The system sensitivity is experimentally determined to be 112 dB. The three-dimensional OCT volumes reveal the structures of the anterior eye segments, which are difficult to observe in two- dimensional OCT images. A two dimensional tomographic movie shows a dynamic motion of a human iris. (c) 2005 Optical Society of America.