Biosynthesis of nanoparticles using microbes-A review
Biosynthesis of nanoparticles using microbes-A review
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DOI：
10.1016/j.colsurfb.2014.05.027
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发表时间：
2014-09-01
影响因子：
5.8
通讯作者：
Taranath, T. C.
中科院分区：
文献类型：
--
作者：
Hulkoti, Nasreen I.;Taranath, T. C.
微生物生物合成纳米颗粒是一项绿色环保技术。本综述重点关注原核生物和真核生物的多种微生物群落用于合成金属纳米颗粒，即银、金、铂、锆、钯、铁、镉和金属氧化物（如氧化钛、氧化锌等）。这些微生物包括细菌、放线菌、真菌和藻类。纳米颗粒的合成可以在细胞内或细胞外进行。几位研究人员报告说，NADH 依赖性硝酸还原酶在金属离子转化为纳米颗粒的过程中发挥着至关重要的作用。 FTIR 研究表明，不同的生物分子（即羧基、伯胺和仲胺、酰胺 I、II 和 III 谱带等）可作为生物还原和封端剂的工具，通过防止团聚和生长来提供颗粒稳定性。纳米颗粒的尺寸和形状随合成过程中所使用的生物体和条件（包括pH、温度和底物浓度）而变化。微生物为纳米粒子的生物合成提供了多样化的环境。这些颗粒安全环保，在医药、农业、化妆品工业、药物输送和生化传感器等领域有广泛应用。补救的挑战包括最佳生产和最短时间获得所需的尺寸和形状，以增强纳米粒子的稳定性以及针对特定应用优化特定微生物。 (C) 2014 Elsevier B.V. 保留所有权利。
The biosynthesis of nanoparticles by microorganism is a green and eco-friendly technology. This review focuses on the use of consortium of diverse microorganisms belonging to both prokaryotes and eukaryotes for the synthesis of metallic nanoparticles viz, silver, gold, platinum, zirconium, palladium, iron, cadmium and metal oxides such as titanium oxide, zinc oxide, etc. These microorganisms include bacteria, actinomycetes, fungi and algae. The synthesis of nanoparticles may be intracellular or extracellular. The several workers have reported that NADH dependent nitrate reductase enzyme plays a vital role in the conversion of metallic ions to nanoparticles. The FTIR study reveals that diverse biomolecules viz, carboxyl group, primary and secondary amines, amide I, II, and III bands etc serve as a tool for bioreduction and capping agents there by offering stability to particles by preventing agglomeration and growth. The size and shape of the nanoparticles vary with the organism employed and conditions employed during the synthesis which included pH, temperature and substrate concentration. The microorganisms provide diverse environment for biosynthesis of nanoparticles. These particles are safe and eco-friendly with a lot of applications in medicine, agriculture, cosmetic industry, drug delivery and biochemical sensors. The challenges for redressal include optimal production and minimal time to obtain desired size and shape, to enhance the stability of nanoparticles and optimization of specific microorganisms for specific application. (C) 2014 Elsevier B.V. All rights reserved.