Dietary Patterns and Risk of Frailty in Chinese Community-Dwelling Older People in Hong Kong: A Prospective Cohort Study.
Dietary Patterns and Risk of Frailty in Chinese Community-Dwelling Older People in Hong Kong: A Prospective Cohort Study.
复制标题
作者：
Chan R;Leung J;Woo J
饮食模式分析是一种新兴的方法来调查饮食和脆弱之间的关联。本研究调查了2724名年龄≥ 65岁的中国社区居民的饮食模式与虚弱的关系。在2001年至2003年期间，使用食物频率问卷收集基线饮食数据。对先验饮食模式的依从性进行了评估，包括国际饮食质量指数（DQI-I）和地中海饮食评分（MDS）。因子分析确定了三种后验膳食模式，即“蔬菜-水果”、“零食-饮料-奶制品”和“肉类-鱼类”。使用FRAIL量表定义事件脆弱性。二进制逻辑回归被用来检查饮食模式和四年的事件脆弱之间的关联。第4年时有31例（1.1%）虚弱事件。在性别和年龄调整模型中，DQI-I每增加10个单位与虚弱风险降低41%相关（比值比（OR）（95%置信区间（CI））：0.59（0.42-0.85），p = 0.004）。在多变量校正模型中，相关性减弱（0.69（0.47-1.02），p = 0.056）。没有观察到其他饮食模式与脆弱性之间的关联。我们的研究表明，以较高的DQI-I为特征的较好的饮食质量与较低的发展脆弱的几率有关。MDS或后天饮食模式对中国老年人虚弱发展的贡献仍有待探讨。
Dietary pattern analysis is an emerging approach to investigate the association between diet and frailty. This study examined the association of dietary patterns with frailty in 2724 Chinese community-dwelling men and women aged ≥ 65 years. Baseline dietary data were collected using a food frequency questionnaire between 2001 and 2003. Adherence to a priori dietary patterns, including the Diet Quality Index-International (DQI-I) and the Mediterranean Diet Score (MDS) was assessed. Factor analysis identified three a posteriori dietary patterns, namely “vegetables-fruits”, “snacks-drinks-milk products”, and “meat-fish”. Incident frailty was defined using the FRAIL scale. Binary logistic regression was applied to examine the associations between dietary patterns and four-year incident frailty. There were 31 (1.1%) incident frailty cases at four years. Every 10-unit increase in DQI-I was associated with 41% reduced risk of frailty in the sex- and age-adjusted model (odds ratio (OR) (95% confidence interval (CI)): 0.59 (0.42–0.85), p = 0.004). The association attenuated in the multivariate adjusted model (0.69 (0.47–1.02), p = 0.056). No association between other dietary patterns and incident frailty was observed. Our study showed that a better diet quality as characterized by higher DQI-I was associated with lower odds of developing frailty. The contribution of MDS or a posteriori dietary patterns to the development of frailty in Chinese older people remains to be explored.