Investigation into the reasons for preventable drug related admissions to a medical admissions unit: observational study
Investigation into the reasons for preventable drug related admissions to a medical admissions unit: observational study
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DOI：
10.1136/qhc.12.4.280
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发表时间：
2003-08-01
影响因子：
--
通讯作者：
Partridge, M
中科院分区：
文献类型：
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作者：
Howard, RL;Avery, AJ;Partridge, M
目的：描述与急性医疗入院病房可预防药物相关入院最常见的药物和药物管理问题类型。设计：观察研究。地点：英国诺丁汉一所教学医院的医疗入院病房。参与者：2001 年 1 月 1 日至 6 月 30 日期间，药剂师在医疗入院病房看诊的 4093 名患者。主要结果指标：与药物相关且可预防的入院比例、药物分类 可预防的药物相关入院的根本原因，以及识别与可预防的药物相关入院最常相关的药物。结果：在药剂师看到的入院中，265 例 (6.5%) 被判断为与药物相关，其中 178 例 (67%) 被判断为可预防。可预防的入院主要是由于处方问题（63例（35%））、监测问题（46例（26%））和服药依从性（53例（30%））。最常涉及的药物是非甾体抗炎药、抗血小板药、抗癫痫药、降血糖药、利尿剂、吸入皮质类固醇、强心苷和β-受体阻滞剂。结论：潜在可预防的药物相关发病率与住院科室入院人数的 4.3% 相关。在 91% 的病例中，这些入院与处方、监测或依从性问题有关。
Objective: To describe the drugs and types of medicine management problems most frequently associated with preventable drug related admissions to an acute medical admissions unit.Design: Observation study.Setting: Medical admissions unit in a teaching hospital in Nottingham, UK.Participants: 4093 patients seen by pharmacists on the medical admissions unit between 1 January and 30 June 2001.Main outcome measures: Proportion of admissions that were drug related and preventable, classification of the underlying causes of preventable drug related admissions, and identification of drugs most commonly associated with preventable drug related admissions.Results: Of the admissions seen by pharmacists, 265 ( 6.5%) were judged to be drug related and 178 (67%) of these were judged to be preventable. Preventable admissions were mainly due to problems with prescribing ( 63 cases (35%)), monitoring ( 46 cases (26%)), and adherence to medication ( 53 cases (30%)). The drugs most commonly implicated were NSAIDs, antiplatelets, antiepileptics, hypoglycaemics, diuretics, inhaled corticosteroids, cardiac glycosides, and beta-blockers.Conclusions: Potentially preventable drug related morbidity was associated with 4.3% of admissions to a medical admissions unit. In 91% of cases these admissions were related to problems with either prescribing, monitoring, or adherence.