PARADOXICAL TIMING OF THE CIRCADIAN-RHYTHM OF SLEEP PROPENSITY SERVES TO CONSOLIDATE SLEEP AND WAKEFULNESS IN HUMANS

PARADOXICAL TIMING OF THE CIRCADIAN-RHYTHM OF SLEEP PROPENSITY SERVES TO CONSOLIDATE SLEEP AND WAKEFULNESS IN HUMANS
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DOI:
10.1016/0304-3940(94)90841-9
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发表时间:
1994-01-17
影响因子:
2.5
通讯作者:
CZEISLER, CA
CZEISLER, CA
中科院分区:
医学4区
文献类型:
--
作者:
DIJK, DJ;CZEISLER, CA

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昼夜节律起搏器和睡眠稳态对睡眠倾向和巩固的贡献是通过昼夜节律起搏器强制使八名男性的睡眠-觉醒周期不同步来量化的,这些男性在时间隔离中生活了 33-36 天。对 175 个测谎记录的睡眠事件的分析表明,昼夜节律起搏器和睡眠稳态对睡眠巩固的贡献大致相同,并且在 24 小时一天中这些振荡过程之间的相位关系具有独特的定时,以促进维持夜间睡眠和全天清醒的能力。
The contribution of the circadian pacemaker and the sleep homeostat to sleep tendency and consolidation was quantified by forced desynchrony of the sleep-wake cycle from the circadian pacemaker in eight men who lived in time-isolation for 33-36 days. Analysis of 175 polygraphically recorded sleep episodes revealed that the circadian pacemaker and the sleep homeostat contribute about equally to sleep consolidation, and that the phase relationship between these oscillatory processes during entrainment to the 24-h day is uniquely timed to facilitate the ability to maintain a consolidated bout of sleep at night and a consolidated bout of wakefulness throughout the day.