Waist-to-thigh ratio with type 2 diabetes can also be a better indicator associated than traditional anthropometrical measurements in Taiwan population
Waist-to-thigh ratio with type 2 diabetes can also be a better indicator associated than traditional anthropometrical measurements in Taiwan population
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DOI：
10.1016/j.annepidem.2005.04.014
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发表时间：
2006-05-01
影响因子：
5.6
通讯作者：
Chiou, Wen-Ko
中科院分区：
文献类型：
--
作者：
Chuang, Yi-Chou;Hsu, Kuang-Hung;Chiou, Wen-Ko
目的：利用三维 (3D) 扫描数据以及其他现有受试者的医疗档案来寻找与 2 型糖尿病 (DM) 相关的更好的人体生理标志物。 方法：在这项为期 3 年期间对 6007 名接受健康检查的受试者进行的横断面研究中，作者采用了数百项身体测量的 3D 扫描数据，并进行了因子分析，以寻找与 2 型糖尿病更好相关的实用指标。使用多元逻辑回归模型来分析指标与 2 型糖尿病存在之间的关联强度。结果：无论肥胖状况如何，从因子分析得出的躯干成分与 2 型糖尿病呈正相关。然而，在同一分层中，下肢成分与 2 型糖尿病呈负相关。因此，腰围被认为是躯干组成部分的实际测量中最强的指标。发现大腿与 2 型糖尿病之间的关联强度在下肢成分的实际测量中最高。腰部与大腿的比率 (WTR) 的标记源自该方法，在与体重指数、腰围或腰臀比进行比较时，该方法被发现是与 2 型糖尿病相关的最佳指标。结论：这项研究提供了一种低成本、无创的实用标记，与 2 型糖尿病的存在更好地相关。经进一步研究，WTR未来可能应用于临床、流行病学研究、预防医学等领域。
PURPOSE: Using three-dimensional (3D) scanning data along with other existing subject's medical profiles to search for better anthropornetric markers in association with type 2 Diabetes Mellitus (DM).METHODS: In this cross-sectional study with 6007 subjects undergoing health examination in a period of 3 years, the authors adopted data from 3D scanning with hundreds of body measures and conducted factor analysis to search for practical indicators better associated with type 2 DM. A multiple logistic regression model was used to analyze strength of association between indicators and presence of type 2 DM.RESULTS: The trunk component derived from factor analysis was positively associated with type 2 DM, regardless of obesity status. However, lower limbs component was found to be negatively associated with type 2 DM in the same stratifications. Waist was thus found as the strongest indicator among practical measures of trunk component. The strength of association between thigh and type 2 DM was found to be the highest among practical measures of lower limbs component. A marker from taking the ratio of waist to thigh (WTR) was derived from the approach which was found to be the best indicator for association with type 2 DM while comparing to body-mass index, waist circumference, or waist-hip ratio.CONCLUSION: This study offers a low-cost, noninvasive practical marker that is better associated with the presence of type 2 DM. WTR, with further study, may be used in clinical practice, epidemiological study, and preventive medicine in the future.