Synthesis and assembly of self-complementary calix[4]arenes
Synthesis and assembly of self-complementary calix[4]arenes
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DOI：
10.1073/pnas.92.26.12403
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发表时间：
1995-12-19
影响因子：
11.1
通讯作者：
Rebek, J
中科院分区：
文献类型：
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作者：
Shimizu, KD;Rebek, J
杯[4]芳烃被设计为可逆二聚化并形成蛋形外壳。组装中的粘合剂相互作用由四个自缔合脲提供，其形成含有16个氢键的环状阵列。从前面描述的O，O ′，O ″，O ″ ′-四苄基杯[4]芳烃分四步完成合成。杯芳烃四脲的二聚化的证据提供了H-1 NMR，质谱，和封装的分子的观察。所得到的空腔具有足够的尺寸以捕获诸如乙苯和对二甲苯的客体。
A calix[4]arene was designed to reversibly dimerize and form an egg-shaped enclosure. Adhesive interactions in the assembly were provided by four self-associating ureas, which form a cyclic array containing 16 hydrogen bonds. The synthesis was completed in four steps from the previously described O,O',O '',O '''-tetrabenzylcalix[4] arene. Evidence for dimerization of the calixarene tetraurea was provided by H-1 NMR, mass spectrometry, and the observation of encapsulated molecules. The resulting cavity was of sufficient size to capture guests such as ethyl benzene and p-xylene.