VASOPRESSIN AND OXYTOCIN RELEASE IN THE BRAIN - A SYNAPTIC EVENT
VASOPRESSIN AND OXYTOCIN RELEASE IN THE BRAIN - A SYNAPTIC EVENT
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DOI：
10.1016/0006-8993(82)90979-9
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发表时间：
1982-01-01
期刊：
影响因子：
2.9
通讯作者：
VANHEERIKHUIZE, JJ
中科院分区：
文献类型：
--
作者：
BUIJS, RM;VANHEERIKHUIZE, JJ
为了获得中枢释放抗利尿激素和催产素的证据，这些肽的释放在大鼠大脑的不同下丘脑外区域被证实。在这些肽能纤维突触终止的区域，抗利尿激素和/或催产素Ca2+依赖性释放，类似于神经垂体，可被K+或缬草碱诱发。这种释放在这些纤维不表现出突触特化的区域中没有发现。
To obtain evidence for a central release of vasopressin and oxytocin, the release of these peptides was demonstrated in various extrahypothalamic areas of the rat brain. In those areas where these peptidergic fibers terminate synaptically a vasopressin and/or oxytocin Ca2+-dependent release, similar to that in the neurohypophysis, could be evoked by K+ or veratridine. Such release was not found in areas in which these fibers do not exhibit synaptic specialization.