An overview of ensembl

An overview of ensembl
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DOI:
10.1101/gr.1860604
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发表时间:
2004-05-01
期刊:
影响因子:
7
通讯作者:
Clamp, M
Clamp, M
中科院分区:
生物学1区
文献类型:
--
作者:
Birney, E;Andrews, TD;Clamp, M

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EnSembl(http://www.ensembl.org/)是一个围绕大基因组序列组织生物信息的生物信息学项目。它是一个稳定的个体基因组自动注释的全面来源,以及它们之间的共性和正构学关系。它也是一个集成任何生物数据的框架,这些数据可以映射到从基因组序列衍生的特征上。EnSembl可以作为一个交互式网站、一组平面文件和一个完整的、可移植的开放源码软件系统来处理基因组。所有数据都是不受限制地提供的,代码是免费提供的。EnSembl的目标是继续“扩大”这种生物整合,以包括与理解人类生物学相关的其他模式生物,因为它们可以获得;“深化”这种整合,以在不同物种的同等成分之间提供更加无缝的联系;并对基因组中以前难以捉摸的功能元件进行进一步分类。
Ensembl (http://www.ensembl.org/) is a bioinformatics project to organize biological information around the sequences of large genomes. It is a comprehensive source of stable automatic annotation of individual genomes, and of the synteny and orthology relationships between them. It is also a framework for integration of any biological data that can be mapped onto features derived from the genomic sequence. Ensembl is available as an interactive Web site, a set of flat files, and as a complete, portable open Source software system for handling genomes. All data are provided without restriction, and code is freely available. Ensembl's aims are to continue to "widen" this biological integration to include other model organisms relevant to understanding human biology as they become available; to "deepen" this integration to provide an ever more seamless linkage between equivalent components in different species; and to provide further classification of functional elements in the genome that have been previously elusive.