Seroprevalence of Toxoplasma gondii in pregnant women and cats in Grenada, West Indies
Seroprevalence of Toxoplasma gondii in pregnant women and cats in Grenada, West Indies
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DOI：
10.1645/ge-762r.1
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发表时间：
2006-06-01
影响因子：
1.3
通讯作者：
Dubey, J. P.
中科院分区：
文献类型：
--
作者：
Asthana, Sumita P.;Macpherson, Calum N. L.;Dubey, J. P.
对西印度群岛格林纳达的534名孕妇和40只家猫的弓形虫抗体流行率进行了研究。用酶联免疫吸附试验(EIA)和改良凝集试验(MAT)分别在人血清和猫血清中寻找弓形虫抗体。57%的孕妇体内发现了抗体。血清阳性率随着年龄的增长而增加；15至19岁的女性中有51%(总计100人)有抗体，而20至24岁的女性中有60%(总计127人)。抗弓形虫抗体(MAT，1：25血清稀释度)的猫占35%，滴度为1：25的猫7只，1：50的猫4只，1：500的猫3只。流行病学数据表明，摄入被卵囊污染的食物或水是弓形虫向妇女传播的重要方式。
Prevalence of antibodies against Toxoplasma gondii was studied in 534 pregnant women and 40 domestic cats in Grenada, West Indies. Antibodies (IgG) for T. gondii were sought in human sera by an enzyme-linked immunosorbent assay and in cat sera by using the modified agglutination test (MAT). Antibodies were found in 57% of pregnant women. Seroprevalence increased with age; 51% of 15- to 19-yr-old women (100 total) had antibodies versus 60% of 20- to 24-yr-old women (127 total). Antibodies to T gondii (MAT, 1:25 serum dilution) were found in 35% of cats; titers were 1:25 in 7 cats, 1:50 in 4 cats, and 1:500 in 3 cats. Epidemiological data suggested that the ingestion of food or water contaminated with oocysts was an important mode of transmission of T. gondii to women.