Criteria of Waist Circumference According to Computed Tomography-Measured Visceral Fat Area and the Clustering of Cardiovascular Risk Factors

Criteria of Waist Circumference According to Computed Tomography-Measured Visceral Fat Area and the Clustering of Cardiovascular Risk Factors
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DOI:
10.1253/circj.cj-09-0183
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发表时间:
2009-10-01
影响因子:
3.3
通讯作者:
Akabayashi, Akira
Akabayashi, Akira
中科院分区:
医学3区
文献类型:
--
作者:
Kashihara, Hidetoshi;Lee, Jung Su;Akabayashi, Akira

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背景:本研究的目的是确定腰围 (WC) 的性别特异性临界值,以检测心血管危险因素 (CCRF) 的聚集,该值反映了日本大量人口的腹内内脏脂肪面积 (VFA)。 方法和结果:研究人群由 6,736 名男性和女性组成,他们在日本东京的 PL 东京医疗保健中心接受定期健康检查并进行计算机断层扫描以进行 VFA 测量。 CCRF 是根据日本代谢综合征标准委员会定义的。使用接收机操作特性分析来测试用于检测 CCRF 的判别值。 VFA 的判别值为男性 103.0 cm(2),敏感性为 68.7%,特异性为 61.8%;女性为 69.0 cm(2),敏感性为 80.8%,特异性为 70.0%。与 VFA 对应的 WC 值男性为 89.1 厘米,女性为 86.3 厘米。 VFA和WC的判别值在有或没有高血压的人之间没有显着差异。结论:为了在初级筛查中早期发现和管理CCRF和VFA,区分和方便的性别特异性WC标准为男性90厘米和女性85厘米。 (Circ J 2009;73:1881 - 1886)
Background: The purpose of this study was to determine the discriminate gender-specific cutoff values of waist circumference (WC) for detecting the clustering of cardiovascular risk factors (CCRF), which reflects the intra-abdominal visceral fat area (VFA) using a large Japanese population.Methods and Results: The study population consisted of 6,736 men and women who underwent a periodic health check-up and had a computed tomography scan for VFA measurement at the PL Tokyo Health Care Center in Tokyo, Japan. The CCRF was defined according to the Japanese Committee of the Criteria for Metabolic Syndrome. The discriminate values for detecting the CCRF were tested using receiver operating characteristics analysis. The discriminate values of VFA were 103.0 cm(2) with 68.7% sensitivity and 61.8% specificity for men and 69.0 cm(2) with 80.8% sensitivity and 70.0% specificity for women. The WC values corresponding to the VFA were 89.1 cm for men and 86.3 cm for women. The discriminate values of VFA and WC were not substantially different between people with or without raised blood pressure.Conclusions: For the early detection and management of the CCRF and VFA in the primary screening setting, the discriminate and convenient gender-specific WC criteria would be 90 cm for men and 85 cm for women. (Circ J 2009; 73: 1881 - 1886)