Catheter-based ultrasound technology for image-guided thermal therapy: current technology and applications.
Catheter-based ultrasound technology for image-guided thermal therapy: current technology and applications.
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DOI：
10.3109/02656736.2015.1006269
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发表时间：
2015-03
期刊：
影响因子：
--
通讯作者：
Diederich CJ
中科院分区：
文献类型：
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作者：
Salgaonkar VA;Diederich CJ
基于导管的超声（CBUS）被应用于实体癌肿瘤、良性组织生长、血管疾病和组织重塑的微创热治疗。与导管手术干预中使用的其他能量模式相比，超声的独特功能导致能量传递一致和精确，具有高选择性，快速治疗时间和更大的治疗量。在这里，简要回顾了目前用于动物和临床研究或正在开发用于未来应用的CBUS技术。CBUS设备可分为间质、腔内和血管/心脏内应用。简要地讨论了基本的涂敷器设计，特定地点的评估和可能的治疗应用。特别强调消融研究，包括应用器放置的图像指导、治疗监测、反馈控制和术后评估。这里包括的设备示例涵盖了从基于初步模拟的设计研究到临床研究实施的整个开发周期。在图像引导下使用CBUS有可能显著提高热治疗输送的精度和适用性。
Catheter-based ultrasound (CBUS) is being applied to deliver minimally invasive thermal therapy to solid cancer tumors, benign tissue growth, vascular disease, and tissue remodeling. Compared to other energy modalities used in catheter-based surgical interventions, unique features of ultrasound result in conformable and precise energy delivery with high selectivity, fast treatment times, and larger treatment volumes. Here, a concise review of CBUS technology being currently utilized in animal and clinical studies or being developed for future applications is presented. CBUS devices have been categorized into interstitial, endoluminal and endovascular/cardiac applications. Basic applicator designs, site specific evaluations and possible treatment applications have been discussed in brief. Particular emphasis has been given on ablation studies that incorporate image-guidance for applicator placement, therapy monitoring, feedback control, and post-procedure assessment. Examples of devices included here span the entire spectrum of development cycle from preliminary simulation based design studies to implementation in clinical investigations. The use of CBUS under image guidance has the potential for significantly improving precision and applicability of thermal therapy delivery.