The Conjugated Auxin Indole-3-Acetic Acid-Aspartic Acid Promotes Plant Disease Development
The Conjugated Auxin Indole-3-Acetic Acid-Aspartic Acid Promotes Plant Disease Development
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DOI：
10.1105/tpc.111.095190
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发表时间：
2012-02-01
期刊：
影响因子：
11.6
通讯作者：
Bouarab, Kamal
中科院分区：
文献类型：
--
作者：
Gonzalez-Lamothe, Rocio;El Oirdi, Mohamed;Bouarab, Kamal
生长素是一种重要的植物激素，对植物的生长发育起着重要的调节作用。众所周知，生长素信号传导会促进植物病原体引起的植物病害。然而，这种激素赋予病原体易感性的机制还不清楚。在这里，我们提出的证据表明，真菌和细菌的植物病原体劫持宿主生长素代谢拟南芥，导致积累的共轭形式的激素，吲哚-3-乙酸（IAA）-天冬氨酸，以促进疾病的发展。我们还表明，IAA-Asp通过调节毒力基因的转录来增加植物中的病原体进展。这些数据突出了一种新的机制，以促进植物对病原体的敏感性，通过生长素共轭。
Auxin is a pivotal plant hormone that regulates many aspects of plant growth and development. Auxin signaling is also known to promote plant disease caused by plant pathogens. However, the mechanism by which this hormone confers susceptibility to pathogens is not well understood. Here, we present evidence that fungal and bacterial plant pathogens hijack the host auxin metabolism in Arabidopsis thaliana, leading to the accumulation of a conjugated form of the hormone, indole-3-acetic acid (IAA)-Asp, to promote disease development. We also show that IAA-Asp increases pathogen progression in the plant by regulating the transcription of virulence genes. These data highlight a novel mechanism to promote plant susceptibility to pathogens through auxin conjugation.