Footstep adjustments used to turn during walking in Parkinson's disease
Footstep adjustments used to turn during walking in Parkinson's disease
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DOI：
10.1002/mds.21932
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发表时间：
2008-04-30
影响因子：
8.6
通讯作者：
Iansek, Robert
中科院分区：
文献类型：
--
作者：
Huxham, Frances;Baker, Richard;Iansek, Robert
帕金森病（PD）患者在行走时的转向经常是个问题。在10名PD患者和10名年龄、性别和身高匹配的对照组中，使用三维运动分析检查了用于转动60度和120度的脚步调整的时空特征。控制科目使用可识别的模式的空间和时间的脚步调制转向。PD参与者在几乎所有变量中表现出显着差异。他们（1）没有像同龄人那样转身;（2）表现出类似但缩小的空间调整模式;（3）走路时使用较短的步幅，转身时夸张地减少;（4）在步伐时间调整方面表现出微小但显着的时间差异。组间差异在较大的转弯处更为显著。空间的结果，解释假设的基底神经节功能障碍，是符合正常的运动命令，但受损的能力，以保持运动幅度。调整步时间的差异，转身可能反映受损的运动时间控制在具有挑战性的步态任务与PD的主题。(C)2008年，《社会运动》创刊。
Turning during walking is frequently problematic in Parkinson's disease (PD). The spatiotemporal characteristics of footstep adjustments used to turn 60 and 120 degrees were examined in 10 people with PD and 10 age, gender- and height-matched control subjects, using three-dimensional motion analysis. Control subjects used a recognizable pattern of spatial and temporal footstep modulations to turn. Participants with PD demonstrated significant differences in almost all variables. They (1) failed to turn as far as their peers; (2) showed a similar but scaled-down pattern of spatial adjustments to turn; (3) used shorter strides when walking, with exaggerated reductions when turning; and (4) demonstrated small but significant temporal differences in step time adjustments. Group differences were more marked for the larger turn. Spatial results, interpreted in light of hypothesized basal ganglia dysfunction, are consistent with a normal motor command but impaired ability to maintain movement amplitude. Differences in adjustment of step time to turn may reflect impaired locomotor timing control in subjects with PD during challenging gait tasks. (C) 2008 Movement Disorder Society.