Biomimetic apatite sintered at very low temperature by spark plasma sintering: Physico-chemistry and microstructure aspects
Biomimetic apatite sintered at very low temperature by spark plasma sintering: Physico-chemistry and microstructure aspects
复制标题
DOI：
10.1016/j.actbio.2009.08.021
复制
发表时间：
2010-02-01
影响因子：
9.7
通讯作者：
Drouet, Christophe
中科院分区：
文献类型：
--
作者：
Grossin, David;Rollin-Martinet, Sabrina;Drouet, Christophe
类似于骨矿物质的纳米晶磷灰石由于其独特的内在物理化学特性，是用于制备高生物活性陶瓷的非常有前途的材料。它们的表面反应性确实与纳米晶体表面上亚稳态水合层的存在有关。然而，通过传统技术在高温下烧结此类磷灰石会强烈改变其物理化学特性和生物特性，这表明需要“更软”的烧结工艺来限制这种改变。在目前的工作中，使用非常规技术——放电等离子体烧结——在非常低的温度（T<300摄氏度）下固结这种纳米晶体磷灰石，以保留纳米晶体上存在的表面水合层。然后通过补充技术对获得的生物陶瓷进行彻底表征。特别是对微观结构、纳米结构和其他主要物理化学特征进行了研究和评论。这项工作增加了当前国际社会对提高现有生物陶瓷性能的关注，旨在为骨组织工程研制新一代可吸收且高生物活性的陶瓷。 (C) 2009 Acta Materialia Inc. 由 Elsevier Ltd 出版。保留所有权利。
Nanocrystalline apatites analogous to bone mineral are very promising materials for the preparation of highly bioactive ceramics due to their unique intrinsic physico-chemical characteristics. Their surface reactivity is indeed linked to the presence of a metastable hydrated layer on the surface of the nanocrystals. Yet the sintering of such apatites by conventional techniques, at high temperature, strongly alters their physico-chemical characteristics and biological properties, which points out the need for "softer" sintering processes limiting such alterations. In the present work a non-conventional technique, spark plasma sintering, was used to consolidate such nanocrystalline apatites at non-conventional, very low temperatures (T < 300 degrees C) so as to preserve the surface hydrated layer present on the nanocrystals. The bioceramics obtained were then thoroughly characterized by way of complementary techniques. In particular, microstructural, nanostructural and other major physico-chemical features were investigated and commented on. This work adds to the current international concern aiming at improving the capacities of present bioceramics, in view of elaborating a new generation of resorbable and highly bioactive ceramics for bone tissue engineering. (C) 2009 Acta Materialia Inc. Published by Elsevier Ltd. All rights reserved.