Nematode neuropeptide receptors and their development as anthelmintic screens
Nematode neuropeptide receptors and their development as anthelmintic screens
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DOI：
10.1017/s003118200500819x
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发表时间：
2005-01-01
期刊：
影响因子：
2.4
通讯作者：
Greary, T
中科院分区：
文献类型：
--
作者：
Greenwood, K;Williams, T;Greary, T
This review addresses the potential use of neuropeptide receptors for the discovery of anthelmintic agents, and particularly for the identification of non-peptide ligands. It outlines which nematode neuropeptides are known and have been characterized, the published information on drug discovery around these targets, information about existing high- and low-throughput screening systems and finally the likely safety of neuropeptide mimetics.
