Distribution of hepatitis B virus genotypes in HIV-infected patients with chronic hepatitis B: therapeutic implications.

Distribution of hepatitis B virus genotypes in HIV-infected patients with chronic hepatitis B: therapeutic implications.
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HIV 感染的慢性乙型肝炎患者中乙型肝炎病毒基因型的分布:治疗意义。

DOI:
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发表时间:
2003
影响因子:
1.5
通讯作者:
V. Soriano
V. Soriano
中科院分区:
医学4区
文献类型:
--
作者:
M. Pérez;M. Nunez;J. García;Pílar Ríos;J. González;V. Soriano

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2002年,我们对在诊所就诊的合并慢性乙肝感染的艾滋病病毒(HIV)感染者进行了乙肝病毒(HBV)基因型检测。在1100人中共有28人(患病率2.5%)被发现乙肝表面抗原(HBsAg)和乙肝病毒脱氧核糖核酸(HBV - DNA)呈阳性。其中23人的HBV基因型可确定。HBV - A型最为常见(57%),其次是HBV - D型(39%)。HBV - A型在同性恋男性中占主导(67%),而HBV - D型在静脉吸毒者中占主导(67%)。血清乙肝e抗原(HBeAg)的存在与HBV - A基因型显著相关。
Hepatitis B virus (HBV) genotypes were examined in HIV-infected patients with chronic HBV infection seen in our clinic during 2002. A total of 28 of 1100 individuals (prevalence 2.5%) were found to be HBsAg and HBV-DNA positive. HBV genotypes could be determined in 23 of them. HBV-A was the most common (57%), followed by HBV-D (39%). HBV-A predominated among homosexual men (67%) while HBV-D predominated among intravenous drug users (67%). The presence of serum HBeAg was significantly associated with the HBV-A genotype.
HIV 感染成人抗逆转录病毒治疗时机的成本效益影响。
DOI: 10.1001/archinte.162.21.2478
发表时间: 2002
影响因子: --
作者:
Schackman,BruceR;Freedberg,KennethA;Weinstein,MiltonC;Sax,PaulE;Losina,Elena;Zhang,Hong;Goldie,SueJ
通讯作者: Goldie,SueJ