Biocompatibility natural effect of rhamnolipids in bioremediation process on different biological systems at the site of contamination
Biocompatibility natural effect of rhamnolipids in bioremediation process on different biological systems at the site of contamination
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DOI：
10.1080/10889868.2018.1516616
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发表时间：
2018-01-01
影响因子：
2
通讯作者：
Sahoo, Dinabandhu
中科院分区：
文献类型：
--
作者：
Bharali, Pranjal;Das, S.;Sahoo, Dinabandhu
已知鼠李糖脂具有降解各种有害和有毒污染物的潜力。然而，缺乏关于其对不同生物系统影响的报告。因此，本研究的重点是评估鼠李糖脂混合物的生物相容性。对小鼠成纤维细胞株（L929）和家兔皮肤表面进行的体外和体内毒性研究表明，鼠李糖脂粗品混合物表现出无毒行为（p < 0.05）。
Rhamnolipid is known for its potential for degradation of various harmful and toxic contaminants. However, there is a lack of reports of their effects on different biological systems. Hence, the present study focuses on the assessment of rhamnolipid mixture for their biocompatibility nature. The in vitro and in vivo toxicity studies on the mouse fibroblast cell line (L929) and rabbit skin surface respectively showed that the crude rhamnolipid mixture exhibits a nontoxic behavior (p