Proton radiation therapy.
Proton radiation therapy.
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质子放射治疗。
作者：
J. Archambeau;G. Bennett;G. Levine;R. Cowen;A. Akanuma
质子治疗的物理，技术，放射学和临床现状进行审查。质子产生的效果类似于x射线，但剂量分布和范围使质子更灵活，更有用的治疗。将质子吸收剂量的主要部分限制在指定体积的能力允许减少对正常组织的剂量或增加对癌症的剂量。通过确定不同治疗计划中x射线与质子的正常组织剂量的比率来量化改进的剂量分布。X射线治疗的正常组织积分剂量通常是质子治疗预期剂量的2至5倍。
Physical, technical, radiological, and clinical status of proton therapy is reviewed. Protons produce effects similar to those of x rays, but dose distribution and range make protons more flexible and useful therapeutically. The ability to confine the major fraction of proton absorbed dose to a designated volume allows the decrease of dose to normal tissue or the increase of dose to the cancer. Improved dose distribution is quantified by determining the ratio of normal tissue dose for x rays to that for protons in different treatment plans. Normal tissue integral dose from x-ray therapy is generally 2 to 5 times as high as that anticipated from proton therapy.