Steric PNP (Poisson-Nernst-Planck): Ions in Channels

Steric PNP (Poisson-Nernst-Planck): Ions in Channels
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位阻 PNP(泊松-能斯特-普朗克):通道中的离子

DOI:
10.1016/j.bpj.2012.11.2809
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发表时间:
2013
影响因子:
3.4
通讯作者:
Chun Liu
Chun Liu
中科院分区:
生物学3区
文献类型:
--
作者:
B. Eisenberg;Tzyy;Tai;Chun Liu

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离子溶液并不理想。所有物质都与其他物质相互作用,特别是在离子通道和活性位点中及其附近的高浓度溶液(> 10 M)中。变分方法(J ChemPhys 133:104104)在相互作用的复杂流体中是需要的。下面的微扰展开的第一项可以在笔记本电脑上在几个小时内产生复杂溶液和通道中的电流电压曲线。方程用多块Chebyshev伪谱方法使用线方法求解(J Computational Physics 231:2498和J Phys Chem B DOI 10.1021-jp 305273 n.
Ionic solutions are not ideal. Everything interacts with everything else, particularly in highly concentrated solutions (> 10 M) in and near ion channels and active sites. A variational approach (J ChemPhys 133: 104104) is needed in interacting complex fluids. The first terms of a perturbation expansion below can produce current voltage curves in complex solutions and channels in a few hours on notebook computers. Equations are solved with multiblock Chebyshev pseudospectral methods using methods of lines (J Computational Physics 231: 2498 and J Phys Chem B DOI 10.1021-jp305273n.
DOI: 10.1016/s0006-3495(00)76446-0
发表时间: 2000-10-01
影响因子: 3.4
作者:
Nonner, W;Catacuzzeno, L;Eisenberg, B
通讯作者: Eisenberg, B
DOI: 10.1016/s0006-3495(98)74048-2
发表时间: 1998-09-01
影响因子: 3.4
作者:
Nonner, W;Eisenberg, B
通讯作者: Eisenberg, B