Monitoring of gallbladder and gastric coordination by EPI
Monitoring of gallbladder and gastric coordination by EPI
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DOI：
10.1002/jmri.20223
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发表时间：
2005-01-01
影响因子：
4.4
通讯作者：
Gowland, PA
中科院分区：
文献类型：
--
作者：
Marciani, L;Bush, D;Gowland, PA
目的：为了评估第一次的潜力，回波平面磁共振成像（EPI）同时测量胆囊和胃empting.Materials和方法：8名健康受试者摄入500毫升的酸稳定的液体测试餐含有15%的橄榄油和调味品。此后每20分钟3小时，一个快速的EPI多层面集被收购在整个腹部，使用一个专用的全身0.5-T EPI scanner.Results：胆囊中的胆汁和胃中的测试餐出现在EPI图像明亮，帮助本地化和感兴趣的分析区域。我们测量了胆囊排空曲线，并将数据拟合到一个简单的分析模型。平均空腹胆囊体积为25 +/- 4 mL，与先前发表的MRI和超声值相当。胃排空数据拟合良好的线性模型线性（R-2 = 0.99），我们观察到的指数（R-2 = 0.98）之间的关系胆囊和胃的体积为第一个90 minutes.Conclusion：这项研究显示了潜在的EPI监测同时和非侵入性的胆囊和胃腔的排空。不需要造影剂。这种方法可以克服以前的伽玛射线照相和超声技术的局限性。
Purpose: To assess for the first time the potential of echo-planar magnetic resonance imaging (EPI) for measuring simultaneously both gallbladder and gastric emptying.Materials and Methods: Eight healthy subjects ingested 500 mL of an acid-stable liquid test meal containing 15% olive oil and flavoring. Every 20 minutes for three hours thereafter, a rapid EPI multislice set was acquired across the whole abdomen, using a dedicated whole-body 0.5-T EPI scanner.Results: The bile in the gallbladder and the test meal in the stomach appeared bright in the EPI images, aiding localization and region of interest analysis. We measured the gallbladder emptying curve and fitted the data to a simple analytical model. The mean fasted gallbladder volume was 25 +/- 4 mL, comparable to previously published MRI and ultrasound values. Gastric emptying data fitted well to a linear model linear (R-2 = 0.99), and we observed an exponential (R-2 = 0.98) relationship between gallbladder and gastric volumes for the first 90 minutes.Conclusion: This study shows the potential of EPI to monitor simultaneously and noninvasively the emptying of the gallbladder and of the gastric lumen. No contrast enhancing agents are needed. This method could overcome the limitations of previous gamma scintigraphy and ultrasound techniques.