The effect of stroke and stroke prophylaxis with aspirin or warfarin on quality of life
The effect of stroke and stroke prophylaxis with aspirin or warfarin on quality of life
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DOI：
10.1001/archinte.156.16.1829
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发表时间：
1996-09-09
影响因子：
--
通讯作者：
Owens, DK
中科院分区：
文献类型：
--
作者：
Gage, BF;Cardinalli, AB;Owens, DK
背景：由于大多数中风引起神经功能损害而不是死亡，预防中风可能改善生活质量而不是延长寿命。因此，了解中风和中风预防如何影响生活质量对许多患者的临床决策至关重要。方法：我们对预期中风的3个严重程度——轻度、中度和重度——以及使用华法林钠或阿司匹林治疗预防中风的情况进行了生活质量评估，即效用评估。我们使用时间权衡和标准赌博方法从83例房颤患者中得出这些效用。结果：70例患者顺利完成访谈。他们对中风的治疗范围从比死亡更糟(
Background: Because most strokes cause neurological impairment rather than death, stroke prophylaxis may improve quality of life more than length of life. Thus, an understanding of how stroke and stroke prophylaxis affect quality of life is central to clinical decision making for many patients.Methods: We elicited quality-of-life estimates, known as utilities, for 3 degrees of severity of anticipated stroke-mild, moderate, and major-and for stroke prophylaxis with either warfarin sodium or aspirin therapy. We used the time tradeoff and standard gamble methods to elicit these utilities from 83 patients who had atrial fibrillation.Results: Seventy patients completed the interview successfully. Their utilities for stroke ranged from worse than death (