Relationship of Prospective Memory to Neuropsychological Function and Antiretroviral Adherence
Relationship of Prospective Memory to Neuropsychological Function and Antiretroviral Adherence
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DOI：
10.1093/arclin/acp046
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发表时间：
2009-09-01
影响因子：
2.6
通讯作者：
Rosen, Marc I.
中科院分区：
文献类型：
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作者：
Contardo, Christopher;Black, Anne C.;Rosen, Marc I.
前瞻性记忆被定义为在未来某个时间“记住记住”某事的能力，尽管干扰干扰，并且可能在记住服用处方药方面对艾滋病毒感染者特别重要。在一项临床试验中，97名HIV阳性参与者通过电子药丸测量其依从性，并进行神经心理学筛查测试和意图记忆筛查测试（MIST）。MIST和其他神经心理学措施的因素分析确定了四个因素。两个来自MIST分量表，约占认知功能方差的50%。只有一个因素与依从性显著相关，这就是MIST因素。在这项初步研究中，MIST评估的记忆功能（a）可以与传统的回顾性回忆和执行功能区分开来，（B）与抗逆转录病毒治疗依从性相关。
Prospective memory is defined as the ability to "remember to remember" something at a future time despite intervening distractions and may be particularly important in remembering to take prescribed medication among people infected with HIV. Ninety-seven HIV-positive participants in a clinical trial had their adherence measured by electronic pillcaps and were administered neuropsychological screening tests and the memory for intentions screening test (MIST). Factor analysis of the MIST and other neuropsychological measures identified four factors. Two were derived from MIST subscales and accounted for approximately 50% of the variance in cognitive functioning. Only one factor was significantly correlated with adherence, and this was a MIST factor. In this preliminary study, the MIST assessed a memory function that (a) could be distinguished from traditional retrospective recall and executive functioning and (b) was correlated with antiretroviral adherence.