Hydrophobic Interactions Modulate Self-Assembly of Nanoparticles
Hydrophobic Interactions Modulate Self-Assembly of Nanoparticles
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DOI：
10.1021/nn3047605
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发表时间：
2012-12-01
期刊：
影响因子：
17.1
通讯作者：
Liz-Marzan, Luis M.
中科院分区：
文献类型：
--
作者：
Sanchez-Iglesias, Ana;Grzelczak, Marek;Liz-Marzan, Luis M.
疏水相互作用是生物系统中最重要的非特异性相互作用之一，当两个疏水物种相互靠近时，水分子重新排列时就会出现这种相互作用。在纳米粒子（布朗物体）水平上预测疏水相互作用仍然具有挑战性，因为不受控制的扩散运动的颗粒。我们在这里描述了一个通用的方法，溶剂诱导的，可逆的自组装成3D团簇的金纳米粒子的大小控制良好。该过程的理论描述证实了疏水相互作用是纳米颗粒聚集背后的主要驱动力。
Hydrophobic interactions constitute one of the most important types of nonspecific interactions in biological systems, which emerge when water molecules rearrange as two hydrophobic species come close to each other. The prediction of hydrophobic interactions at the level of nanoparticles (Brownian objects) remains challenging because of uncontrolled diffusive motion of the particles. We describe here a general methodology for solvent-induced, reversible self-assembly of gold nanoparticles into 3D clusters with well-controlled sizes. A theoretical description of the process confirmed that hydrophobic interactions are the main driving force behind nanopartide aggregation.