Lighting up H2O2: The Molecule that Is a "Necessary Evil" in the Cell
Lighting up H2O2: The Molecule that Is a "Necessary Evil" in the Cell
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DOI：
10.1002/anie.200805651
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发表时间：
2009-01-01
影响因子：
16.6
通讯作者：
Zhao, Wei
中科院分区：
文献类型：
--
作者：
Zhao, Wei
一个狡猾的计划：在多功能荧光探针MitoPY 1中，鳞头基（红色）靶向线粒体，硼酸酯基（绿色）响应过氧化氢。MitoPY1在活细胞中选择性地与线粒体H2O2反应，并且通过MitoPY1转化为MitoPY1ox（黄色）触发荧光增加。
A cunning plan: In the multifunctional fluorescent probe MitoPY1 the phosphonium head group (red) targets mitochondria and the boronate group (green) responds to hydrogen peroxide. MitoPY1 reacts selectively with mitochondrial H2O2in living cells, and an increase in fluorescence is triggered by the conversion of MitoPY1 into MitoPY1ox (yellow).