The clustering of physical health conditions and associations with co-occurring mental health problems and problematic alcohol use: a cross-sectional study.
The clustering of physical health conditions and associations with co-occurring mental health problems and problematic alcohol use: a cross-sectional study.
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身体健康状况的聚类以及与精神健康问题和有问题的酒精使用的关联：一项横断面研究。
DOI：
10.1186/s12888-023-04577-3
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发表时间：
2023-02-06
期刊：
影响因子：
4.4
通讯作者：
中科院分区：
文献类型：
--
作者：
有强有力的证据表明，精神健康状况和酒精问题同时发生，但这一群体的身体健康结果还没有得到很好的表征。本研究旨在确定身体健康状况的集群及其与心理健康和有问题的酒精使用在英格兰的一般人群的关联。对2014年成人精神病发病率调查（N = 7546）进行了横断面分析。该调查使用了有问题的酒精使用和心理健康状况的标准化措施，包括酒精使用障碍识别测试（AUDIT）和临床访谈计划修订版。参与者自我报告任何终身身体健康状况。潜在类别分析考虑了12种常见的身体疾病，以确定多发病的集群。使用多项逻辑回归（调整年龄，性别，种族，教育和职业等级）来探索心理健康，危险饮酒（AUDIT 8 +）和共同发生的身体疾病之间的关联。五个聚类被确定为具有统计学上不同的和临床上有意义的疾病模式：“身体健康”（76.62%），“新兴的多发性硬化症”（3.12%），“高血压和关节炎”（14.28%），“消化和肠道问题”（3.17%）和“复杂的多发性硬化症”（2.8%）。有心理健康问题与“消化和肠道问题”（调整后的多项比值比（AMOR）= 1.58; 95%CI [1.15-2.17]）和“复杂多项疾病”（AMOR = 2.02; 95%CI [1.49-2.74]）的几率增加有关。同时患有精神健康状况和有问题的酒精使用的个体也有更高的“消化和肠道问题”（AMOR = 2.64; 95%CI [1.68-4.15]）和“复杂的多发病”（AMOR = 2.62; 95%CI [1.61-4.23]）的几率。患有精神健康状况同时又有酗酒问题的个人会经历更大的身体疾病负担，这突出表明需要及时治疗，这可能包括更好地将酗酒和精神健康服务结合起来。在线版本包含补充材料，可通过10.1186/s12888-023-04577-3获得。
There is strong evidence for the co-occurrence of mental health conditions and alcohol problems, yet physical health outcomes among this group are not well characterised. This study aimed to identify clusters of physical health conditions and their associations with mental health and problematic alcohol use in England’s general population. Cross-sectional analysis of the 2014 Adult Psychiatric Morbidity Survey (N = 7546) was conducted. The survey used standardised measures of problematic alcohol use and mental health conditions, including the Alcohol Use Disorders Identification Test (AUDIT) and the Clinical Interview Schedule-Revised. Participants self-reported any lifetime physical health conditions. Latent class analysis considered 12 common physical illnesses to identify clusters of multimorbidity. Multinomial logistic regression (adjusting for age, gender, ethnicity, education, and occupational grade) was used to explore associations between mental health, hazardous drinking (AUDIT 8 +), and co-occurring physical illnesses. Five clusters were identified with statistically distinct and clinically meaningful disease patterns: ‘Physically Healthy’ (76.62%), ‘Emerging Multimorbidity’ (3.12%), ‘Hypertension & Arthritis’ (14.28%), ‘Digestive & Bowel Problems’’ (3.17%), and ‘Complex Multimorbidity’ (2.8%). Having a mental health problem was associated with increased odds of ‘Digestive & Bowel Problems’ (adjusted multinomial odds ratio (AMOR) = 1.58; 95% CI [1.15–2.17]) and ‘Complex Multimorbidity’ (AMOR = 2.02; 95% CI [1.49–2.74]). Individuals with co-occurring mental health conditions and problematic alcohol use also had higher odds of ‘Digestive & Bowel Problems’ (AMOR = 2.64; 95% CI [1.68–4.15]) and ‘Complex Multimorbidity’ (AMOR = 2.62; 95% CI [1.61–4.23]). Individuals with a mental health condition concurrent with problematic alcohol use experience a greater burden of physical illnesses, highlighting the need for timely treatment which is likely to include better integration of alcohol and mental health services. The online version contains supplementary material available at 10.1186/s12888-023-04577-3.
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影响因子：
2.8
作者：
König HH;Leicht H;Bickel H;Fuchs A;Gensichen J;Maier W;Mergenthal K;Riedel-Heller S;Schäfer I;Schön G;Weyerer S;Wiese B;Bussche Hv;Scherer M;Eckardt M;MultiCare study group
通讯作者：
MultiCare study group
影响因子：
4.5
作者：
John, Ann;McGregor, Joanna;Lloyd, Keith
通讯作者：
Lloyd, Keith
影响因子：
3
作者：
AKAIKE, H
通讯作者：
AKAIKE, H
影响因子：
5.5
作者：
Boyd, Cynthia M.;Fortin, Martin
通讯作者：
Fortin, Martin
影响因子：
6
作者：
Liang, Wenbin;Chikritzhs, Tanya
通讯作者：
Chikritzhs, Tanya