Middle East respiratory syndrome coronavirus (MERS-CoV) in dromedary camels, Oman, 2013
Middle East respiratory syndrome coronavirus (MERS-CoV) in dromedary camels, Oman, 2013
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DOI：
10.2807/1560-7917.es2014.19.16.20781
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发表时间：
2014-04-24
期刊：
影响因子：
19
通讯作者：
Kolodziejek, J.
中科院分区：
文献类型：
--
作者：
Nowotny, N.;Kolodziejek, J.
阿曼的一项全国性调查显示，76头单峰骆驼中有5头携带中东呼吸综合征冠状病毒（MERS-CoV）核酸。来自阿曼和卡塔尔的骆驼来源MERS-CoV序列（由开放阅读框（ORF）1a、刺突和ORF 4 b基因的部分序列组装而成的3，754个核苷酸）彼此略有不同，但与来自相同地理区域的人类MERS-CoV序列密切相关，表明局部人畜共患传播。鼻和结膜拭子中的高病毒载量表明可能通过呼吸道途径传播。
A countrywide survey in Oman revealed Middle East respiratory syndrome coronavirus (MERS-CoV) nucleic acid in five of 76 dromedary camels. Camel-derived MERS-CoV sequences (3,754 nucleotides assembled from partial sequences of the open reading frame (ORF)1a, spike, and ORF4b genes) from Oman and Qatar were slightly different from each other, but closely related to human MERS-CoV sequences from the same geographical areas, suggesting local zoonotic transmission. High viral loads in nasal and conjunctival swabs suggest possible transmission by the respiratory route.