An approach for practical multiobjective IMRT treatment planning
An approach for practical multiobjective IMRT treatment planning
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DOI：
10.1016/j.ijrobp.2007.08.019
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发表时间：
2007-12-01
影响因子：
7
通讯作者：
Bortfeld, Thomas
中科院分区：
文献类型：
--
作者：
Craft, David;Halabi, Tarek;Bortfeld, Thomas
目的：介绍和演示一个实用的多目标治疗计划程序的调强放射治疗（IMRT）planning.Methods和Materials：帕累托最优治疗计划的数据库的创建分为两个步骤。第一步解决优化问题，找到接近一组临床愿望的单个治疗计划。这个计划提供了一个可行的例子，然后用于确定计划数据库的后续生成的相互满足的硬约束。所有的优化都是使用线性programming.Results：两步程序被应用到大脑，前列腺和肺的情况下。创建的计划数据库允许选择一个最终的治疗计划的基础上观察到的各种器官之间的权衡involved.Conclusions：所提出的方法减少了人类的迭代时间常见的调强放射治疗计划。此外，计划的数据库，当正确地查看，允许决策者作出知情的最终计划选择。(c)2007年爱思唯尔公司
Purpose: To introduce and demonstrate a practical multiobjective treatment planning procedure for intensity-modulated radiation therapy (IMRT) planning.Methods and Materials: The creation of a database of Pareto optimal treatment plans proceeds in two steps. The first step solves an optimization problem that finds a single treatment plan which is close to a set of clinical aspirations. This plan provides an example of what is feasible, and is then used to determine mutually satisfiable hard constraints for the subsequent generation of the plan database. All optimizations are done using linear programming.Results: The two-step procedure is applied to a brain, a prostate, and a lung case. The plan databases created allow for the selection of a final treatment plan based on the observed tradeoffs between the various organs involved.Conclusions: The proposed method reduces the human iteration time common in IMRT treatment planning. Additionally, the database of plans, when properly viewed, allows the decision maker to make an informed final plan selection. (c) 2007 Elsevier Inc.