Hemidystonia secondary to thalamic hemorrhage treated with GPi stimulation
Hemidystonia secondary to thalamic hemorrhage treated with GPi stimulation
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DOI：
10.1002/mds.22183
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发表时间：
2008-09-15
影响因子：
8.6
通讯作者：
Kuratsu, Jun-ichi
中科院分区：
文献类型：
--
作者：
Hamasaki, Tadashi;Yamada, Kazumichi;Kuratsu, Jun-ichi
继发性偏侧肌张力的手术治疗报道较少，大多数是由于基底节卒中或外伤所致。我们报告了2例继发于丘脑出血的偏侧肌张力障碍患者，我们成功地用单侧苍白球内（GPi）刺激治疗。病例1为一位56岁男性，有异常姿势及左手臂无法忍受的肌肉收缩疼痛;病例2为一位73岁女性，因右手臂过度伸展而出现严重异常姿势及步态障碍。两名患者的肌张力障碍症状均为药物难治性。在高频GPi刺激开始后3个月，病例1和病例2的Burke-Fahn-Marsden肌张力障碍评定量表的运动评分分别改善了49.2%和34.3%。我们建议GPi刺激作为一种可能的替代治疗继发性偏侧肌张力。(C)2008年，《社会运动》创刊。
There have been few reports on the surgical treatment of secondary hemidystonias, most of which are due to basal ganglia stroke or trauma. We present 2 patients with hemidystonia secondary to thalamic hemorrhage whom we successfully treated with unilateral globus pallidus internus (GPi) stimulation. Case 1 is a 56-year-old man with abnormal posturing and intolerable muscle contraction pain in the left arm. Case 2 is a 73-year-old woman who developed severe abnormal posturing in the right arm and gait disturbance due to hyperextension of the right leg. The dystonic symptoms of both patients were refractory to medication. Three months after the inception of high frequency GPi stimulation, the motor scores on the Burke-Fahn-Marsden Dystonia Rating Scale were improved by 49.2% and 34.3% in Cases 1 and 2, respectively. We suggest GPi stimulation as a possible alternative to treat secondary hemidystonia. (C) 2008 Movement Disorder Society.