Intrahepatic Cholangiocarcinoma
Intrahepatic Cholangiocarcinoma
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DOI：
10.1016/j.suc.2010.04.011
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发表时间：
2010-08-01
影响因子：
3.1
通讯作者：
Pawlik, Timothy M.
中科院分区：
文献类型：
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作者：
Poultsides, George A.;Zhu, Andrew X.;Pawlik, Timothy M.
肝内胆管癌 (ICC) 是胆管的原发性癌症，由胆管内壁上皮细胞的恶性转化引起。ICC 相对不常见，但其发病率呈上升趋势。ICC 经常被发现是一种偶然的、不确定的肝脏肿块。手术切除 ICC 是唯一可能治愈的治疗选择。常规肺门淋巴结切除术的作用存在争议，但应考虑优化分期。尽管目前的数据可能不支持辅助化疗和放疗，但对于淋巴结转移或 R1 切除的患者，应强烈考虑每种治疗。对于无法手术的患者，可以考虑经动脉化疗栓塞局部治疗
Intrahepatic cholangiocarcinoma (ICC) is a primary cancer of the bile ducts, arising from malignant transformation of the epithelial cells that line the biliary apparatus ICC is relatively uncommon, but its incidence is on the increase ICC is frequently discovered as an incidental, indeterminate liver mass Surgical resection of ICC represents the only potentially curative therapeutic option. The role of routine hilar lymphadenectomy is controversial, but should be considered to optimize staging Although adjuvant chemotherapy and radiotherapy is probably not supported by current data, each should strongly be considered in patients with lymph node metastasis or an R1 resection. For those patients with inoperable disease, locoregional therapy with transarterial chemoembolization can be considered