Study on cavitation behavior during high-intensity focused ultrasound exposure by using optical and ultrasonic imaging
Study on cavitation behavior during high-intensity focused ultrasound exposure by using optical and ultrasonic imaging
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DOI：
10.7567/jjap.55.07kf22
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发表时间：
2016-07-01
影响因子：
1.5
通讯作者：
Umemura, Shin-ichiro
中科院分区：
文献类型：
--
作者：
Taguchi, Kei;Takagi, Ryo;Umemura, Shin-ichiro
众所周知，空化气泡可以增强高强度聚焦超声（HIFU）的加热效果。在我们之前的研究中，提出了使用由高强度脉冲和相对低强度爆发组成的“触发HIFU”序列作为利用空化气泡效应的有效方法。然而，序列中每个组件的持续时间并没有得到优化。在本研究中，通过光学成像来观察在触发HIFU暴露期间凝胶幻影中的空化气泡的行为。利用脉冲反演方法进行超声成像，检测气泡的行为。结果表明，随着HIFU爆发暴露时间的增加，空化气泡的振荡趋于不活跃，达到10ms数量级。研究还表明，超声成像有可能用于检测空化气泡振荡的变化，以优化触发HIFU序列。(C) 2016 .日本应用物理学会
Cavitation bubbles are known to enhance the heating effect of high-intensity focused ultrasound (HIFU). In our previous study, the use of a "triggered HIFU" sequence consisting of a high-intensity pulse and a relatively low-intensity burst was proposed as an effective method to utilize the effect of cavitation bubbles. However, the duration of each component in the sequence has not been optimized. In this study, optical imaging was carried out to observe the behavior of cavitation bubbles in a gel phantom during the triggered HIFU exposure. Ultrasound imaging using the pulse inversion method was also conducted to detect the behavior of the bubbles. The results suggest that the oscillation of cavitation bubbles become inactive as the duration of HIFU burst exposure increases to the order of 10ms. It was also suggested that ultrasonic imaging has potential use for detecting a change in the oscillation of cavitation bubbles for optimizing a triggered HIFU sequence. (C) 2016 The Japan Society of Applied Physics