Quantitative radionuclide angiocardiography. Determination of left ventricular ejection fraction in children.
Quantitative radionuclide angiocardiography. Determination of left ventricular ejection fraction in children.
复制标题
定量放射性核素血管造影。
作者：
D. Kurtz;D. S. Ahnberg;M. Freed;C. Lafarge;S. Treves
本文介绍了一种测量左心室射血分数的方法，该方法采用高频计算机记录伽马闪烁相机数据，并以高锝酸钠的形式外周静脉注射锝-99m。力学模型实验数据表明了该方法的可行性。本文描述了一种用于开发在背景存在下准确描绘心室轮廓的技术的幻影实验。12例患者采用核素血管造影和双翼血管造影测量左心室射血。两种方法的相关系数为0 ~ 91。此外，34例无心脏病证据的患者（年龄7周至18岁）使用放射性核素法单独测量左心室射血分数。2岁以上儿童和2岁以下儿童的平均射血分数分别为0 ~ 66分和0 ~ 70分。此外，对10例患者的数据进行了观察者间比较研究，仅发现微小差异（SD 0-025）。
A method is described for measuring left ventricular ejection fraction which uses high frequency computer recording of gamma scintillation camera data and peripheral venous injectinon of technetium-99m as sodium pertechnetate. Data from mechanical model experiments are used to show feasibility of this method. A phantom experiment is described which was used to develop a technique for accurate delineation of the ventricular outline in the presence of background. The left ventricular ejection was measured in 12 patients by radionuclide angiocardiography and biplane cineangiography. Comparison of these two methods gave a correlation coefficient of 0-91. In addition, left ventricular ejection fraction was measured in 34 patients (aged 7 weeks to 18 years) without evidence of cardiac disease using the radionuclide method alone. Average ejection fractions of 0-66 and 0-70 were found for children over 2 years of age and children 2 years of age or younger, respectively. In addition, an interobseerver comparison study was performed with the data from 10 patients, and only small differences were noted (SD 0-025).