Salicylic acid modulates colonization of the root microbiome by specific bacterial taxa
Salicylic acid modulates colonization of the root microbiome by specific bacterial taxa
复制标题
DOI：
10.1126/science.aaa8764
复制
发表时间：
2015-08-21
期刊：
影响因子：
56.9
通讯作者：
Dangl, Jeffery L.
中科院分区：
文献类型：
--
作者：
Lebeis, Sarah L.;Paredes, Sur Herrera;Dangl, Jeffery L.
免疫系统区分“自身”和“非自身”以维持体内平衡，并且必须差异化地控制进入以允许潜在有益的非病原性微生物定植。植物根在极其多样化的土壤微生物群落中生长，但组装了分类学上有限的根相关微生物组。我们在野生土壤中以及合成细菌群落的再定殖实验中培育了具有改变的免疫系统的同基因拟南芥突变体。我们确定，叶面防御植物激素水杨酸的生物合成和信号传导依赖于叶面防御植物激素水杨酸，是组装正常根部微生物组所必需的。水杨酸调节特定细菌家族在根部的定植。因此，植物免疫信号驱动从可用的微生物群落中进行选择，以塑造根微生物组。
Immune systems distinguish "self" from "nonself" to maintain homeostasis and must differentially gate access to allow colonization by potentially beneficial, nonpathogenic microbes. Plant roots grow within extremely diverse soil microbial communities but assemble a taxonomically limited root-associated microbiome. We grew isogenic Arabidopsis thaliana mutants with altered immune systems in a wild soil and also in recolonization experiments with a synthetic bacterial community. We established that biosynthesis of, and signaling dependent on, the foliar defense phytohormone salicylic acid is required to assemble a normal root microbiome. Salicylic acid modulates colonization of the root by specific bacterial families. Thus, plant immune signaling drives selection from the available microbial communities to sculpt the root microbiome.