The cerebellar projections to the superior colliculus and pretectum in the cat: An autoradiographic and horseradish peroxidase study
The cerebellar projections to the superior colliculus and pretectum in the cat: An autoradiographic and horseradish peroxidase study
复制标题
猫的小脑对上丘和顶盖的投射：放射自显影和辣根过氧化物酶研究
DOI：
10.1016/0306-4522(82)90026-4
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发表时间：
1982
期刊：
影响因子：
3.3
通讯作者：
T. Matsuyama
中科院分区：
文献类型：
--
作者：
S. Kawamura;S. Hattori;Shigeyoshi Higo;T. Matsuyama
从小脑核的传出投射的上级丘和顶盖前已研究使用逆行和顺行标记技术在猫。为了确定小脑核的哪些部分项目的上级丘和顶盖前，采用逆行辣根标记技术。在另一组实验中，将氚化氨基酸注射到小脑顶盖和小脑顶盖前投射的小脑区域，比较了上级丘和顶盖前的顺向标记的层和空间分布，结果表明小脑顶盖投射来自小脑核的两个不同区域：内侧核的尾侧半部分和后间置核的腹外侧部分。起源于内侧核的纤维分布于两侧上级中间灰层的浅部，而起源于后间核的纤维则终止于对侧中间灰层的深部及深灰色和白色层。虽然外侧核不参与小脑顶盖投射，但它向对侧顶盖前区投射丰富。小脑顶盖前投射的起源位于外侧核的小细胞部。在顶盖前核团中，顶盖前后核、顶盖前内侧核和顶盖前前核网状部接受小脑的传入，小脑向上级丘和顶盖前核的差异投射表明，小脑通过差异回路对这些中脑结构的视觉-运动和躯体-运动传递发挥调节作用。
Efferent projections from the cerebellar nuclei to the superior colliculus and the pretectum have been studied using both retrograde and orthograde labeling techniques in the cat. In order to identify what parts of the cerebellar nuclei project to the superior colliculus and the pretectum, the retrograde horseradish labeling technique was employed. In another set of experiments, tritiated amino acids were injected into each of the cerebellar regions from which the cerebello-tectal and cerebellopretectal projections arise, and the laminar and spatial distributions of orthograde labeling in the superior colliculus and the pretectum were compared.The results showed that the cerebello-tectal projections arise from two different regions of the cerebellar nuclei: the caudal half of the medial nucleus and the ventrolateral part of the posterior interposed nucleus. Fibers arising from the medial nucleus distribute bilaterally in the superficial zone of the intermediate gray layer in the superior colliculus, while those originating from the posterior interposed nucleus terminate contralaterally in the deeper aspect of the intermediate gray layer and in the deep gray and white layers. Although the lateral nucleus does not contribute to the cerebello-tectal projection, it projects profusely to the pretectum contralaterally. The origin of the cerebello-pretectal projection lies in the parvicellular part of the lateral nucleus. Among several pretectal nuclei, the posterior pretectal, the medial pretectal nucleus and the reticular part of the anterior pretectal nucleus receive the cerebellar afferents.The findings of the differential projections from the cerebellum to the superior colliculus and the pretectum suggest that the cerebellum exerts a regulatory influence on visuo-motor and somato-motor transfer in these midbrain structures by differential circuits.