Culture of Neural Cells and Stem Cells on Graphene
Culture of Neural Cells and Stem Cells on Graphene
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DOI：
10.1007/s13770-013-0384-6
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发表时间：
2013-04-01
影响因子：
3.6
通讯作者：
Kim, Byung-Soo
中科院分区：
文献类型：
--
作者：
Ryu, Seungmi;Kim, Byung-Soo
石墨烯作为一种新型的具有潜在生物相容性的生物材料，具有高电导率、高弹性和良好的分子吸附等特性。它具有广泛的生物医学应用的巨大潜力。尽管基于石墨烯的纳米材料的研究仍处于初级阶段，但石墨烯已经成为组织工程和再生医学中共同感兴趣的问题。在这篇综述中，我们总结了石墨烯可能对细胞产生生物效应的特性。我们详细讨论了石墨烯应用于神经细胞和干细胞的探索；它如何影响细胞行为和分化。然后，我们介绍了石墨烯及其衍生物的细胞毒性研究结果。
Graphene, as a new potential biocompatible biomaterial, retains some unique properties such as high electrical conductivity, elasticity and good molecule absorption. It has tremendous potential for a wide variety of biomedical applications. Even though studies on graphene-based nanomaterials are still at a nascent stage, graphene has been a matter of common interest in tissue engineering and regenerative medicine. In this review, we summarize the characteristics of graphene that could impose biological effects on cells. We discuss in detail the exploration of graphene when applied on neural cells and stem cells; how it affects cell behavior and differentiation. We then present the results from cytotoxicity studies on graphene and its derivatives.