Anterior and superior lateral occipito-temporal cortex responsible for target motion prediction during overt and covert visual pursuit
Anterior and superior lateral occipito-temporal cortex responsible for target motion prediction during overt and covert visual pursuit
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DOI：
10.1016/j.neures.2005.10.015
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发表时间：
2006-02-01
影响因子：
2.9
通讯作者：
Kawato, M
中科院分区：
文献类型：
--
作者：
Kawawaki, D;Shibata, T;Kawato, M
在增益接近1的平滑追踪眼球运动（SPEM）中，由于视网膜滑动接近于零，因此SPEM主要通过预测目标运动来控制。我们通过这三个fMRI实验研究了视觉目标预测的神经机制。(1)外显追踪任务：被试追踪一个正弦运动的目标，该目标眨眼（眨眼条件）或不眨眼（连续条件）。(2)内隐追踪任务：被试注视注视点，对同一目标进行内隐追踪。(3)注意固定目标任务：被试将注意力集中在固定目标上，眼睛注视固定点。在明显的追求任务，SPEM增益和延迟在眨眼条件下没有很大的不同，从连续的条件下，表明良好的预测闪烁的目标运动。在眨眼连续减影中，背外侧前额叶、中央前额叶、内侧上级额叶、顶内皮层和外侧枕颞皮层的活动增加。V1活性在这种对比下降低。在内隐追踪任务中，只有前/上级低活性保留在眨眼连续减法。在注意固定目标任务中，眨眼连续减法没有引起激活。因此，a/sLOTC活动负责目标预测，而不是眼睛运动的运动命令或仅仅是目标眨眼，如视觉显著性。(c)2005年Elsevier爱尔兰有限公司和日本神经科学学会。All rights reserved.
In smooth-pursuit eye movements (SPEM) with gain close to one, SPEM should be controlled mainly by prediction of target motion because retinal slip is nearly zero. We investigated the neural mechanisms of visual-target prediction by the three fMRI experiments. (1) Overt pursuit task: subjects pursued a sinusoidally moving target which blinked (blink condition) or did not blink (continuous condition). (2) Covert pursuit task: subjects covertly pursued the same target with eyes gazed at fixation point. (3) Attend-to-stationary target task: subjects brought attention on a stationary target with eyes gazed at fixation point. In the overt pursuit task, the SPEM gain and the delay in the blink condition were not very different from the continuous condition, indicating good prediction of the blinking target motion. Activities in the dorsolateral prefrontal, precentral, medial superior frontal, intraparietal, and lateral occipito-temporal cortexes increased in the blink-continuous subtraction. The V1 activity decreased for this contrast. In the covert pursuit task, only the anterior/superior LOW activity remained in the blink-continuous subtraction. In the attend-to-stationary target task, the blink-continuous subtraction elicited no activation. Consequently, the a/sLOTC activity is responsible for target prediction rather than motor commands for eye movements or just target blinking such as visual saliency. (c) 2005 Elsevier Ireland Ltd and the Japan Neuroscience Society. All rights reserved.