Effects of an intensive weight loss program on knee joint loading in obese adults with knee osteoarthritis

Effects of an intensive weight loss program on knee joint loading in obese adults with knee osteoarthritis
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DOI:
10.1016/j.joca.2011.03.006
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发表时间:
2011-07-01
影响因子:
7
通讯作者:
Henriksen, M.
Henriksen, M.
中科院分区:
医学2区
文献类型:
--
作者:
Aaboe, J.;Bliddal, H.;Henriksen, M.

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目的:探讨强化减肥对肥胖膝关节骨性关节炎(OA)患者步行过程中膝关节负荷的影响。方法:研究对象为157例接受16周饮食干预的肥胖膝骨性关节炎患者。在干预前后以参与者自由选择的步行速度进行三维步态分析。计算膝关节压缩力、轴向推力、膝关节屈曲角度以及膝关节额面和矢状面的膝关节力矩,以确定减肥的生物力学效应。结果:157名受试者(占初始队列的89%)完成了为期16周的干预。平均体重下降13.7 kg(P
Objective: To determine the effect of an intensive weight loss program on knee joint loads during walking in obese patients with knee osteoarthritis (OA).Methods: Participants included 157 obese knee OA patients that underwent a 16-week dietary intervention. Three-dimensional gait analyses were performed before and after the intervention at the participants' freely chosen walking speed. Knee joint compression forces, axial impulses, knee flexion angle and frontal and sagittal plane knee moments were calculated to determine the biomechanical effects of the weight loss.Results: 157 subjects (89% of the initial cohort) completed the 16-week intervention. The average weight loss of 13.7 kg (P