Fishing for the signals that pattern the face.
Fishing for the signals that pattern the face.
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DOI：
10.1186/jbiol205
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发表时间：
2009
影响因子：
--
通讯作者：
Le Pabic P
中科院分区：
文献类型：
--
作者：
Schilling TF;Le Pabic P
斑马鱼是研究形成头骨和面部的早期胚胎事件的强大系统，作为人类颅面出生缺陷（如腭裂）的模型。信号通路的图案咽弓（其中包含骨骼前体的腭，以及颌骨和鳃）的讨论，根据最近的一篇论文在BMC发育生物学的要求刺猬信号在颅面发育。参见研究文章http://www.biomedcentral.com/1471-213X/9/59
Zebrafish are a powerful system for studying the early embryonic events that form the skull and face, as a model for human craniofacial birth defects such as cleft palate. Signaling pathways that pattern the pharyngeal arches (which contain skeletal precursors of the palate, as well as jaws and gills) are discussed in light of a recent paper in BMC Developmental Biology on requirements for Hedgehog signaling in craniofacial development. See research article http://www.biomedcentral.com/1471-213X/9/59