Weight loss, behavioral change, and structural neuroplasticity in children with obesity through a multidisciplinary treatment program
Weight loss, behavioral change, and structural neuroplasticity in children with obesity through a multidisciplinary treatment program
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DOI：
10.1002/hbm.24360
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发表时间：
2019-01-01
影响因子：
4.8
通讯作者：
Caeyenberghs, Karen
中科院分区：
文献类型：
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作者：
Augustijn, Mireille J. C. M.;D'Hondt, Eva;Caeyenberghs, Karen
本研究评估了多学科治疗计划对肥胖儿童（OB）运动能力、执行功能（EF）和大脑结构的影响。19名OB儿童（7-11岁）参加了由饮食限制，认知行为治疗和体力活动组成的多学科治疗计划，与年龄匹配的24名健康体重（HW）儿童对照组进行了比较，他们没有接受任何治疗。对于两组，进行了两次人体测量以及运动能力和EF测试，前后测试间隔5个月。此外，儿童的大脑结构进行了评估，在测试前和测试后，其中包括T1解剖扫描，磁共振成像（MRI）扫描，扩散MRI扫描和磁化传递成像扫描。与HW对照组相比，OB儿童的体重减少了相当多（p
This study evaluated the effect of a multidisciplinary treatment program for children with obesity (OB) on motor competence, executive functioning (EF), and brain structure. Nineteen children with OB (7-11 years), who attended a multidisciplinary treatment program consisting of diet restriction, cognitive behavioral therapy, and physical activity, were compared with an age-matched control group of 24 children with a healthy weight (HW), who did not follow any treatment. For both groups, anthropometric measurements and tests of motor competence and EF were administered twice, with 5 months between pretest and posttest. Additionally, children's brain structure was assessed by performing a magnetic resonance imaging (MRI) scan at the pretest and posttest, which included a T1 anatomical scan, diffusion MRI scan, and magnetization transfer imaging scan. Compared to HW controls, children with OB lost a considerable amount of their body mass (p