The mental number line and the human angular gyrus
The mental number line and the human angular gyrus
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DOI：
10.1006/nimg.2001.0927
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发表时间：
2001-12-01
期刊：
影响因子：
5.7
通讯作者：
Rushworth, MFS
中科院分区：
文献类型：
--
作者：
Göbel, S;Walsh, V;Rushworth, MFS
为了研究人脑中与语言无关的数字大小空间表征的大脑半球组织，我们对右侧或左侧角回进行了焦点重复经颅磁刺激(RTMS)，同时受试者进行了数字比较任务，数字范围在31到99之间。角回上的重复TMS干扰了视觉空间搜索任务的执行，而同一地点的rTMS破坏了假定的“数字线”的组织。在某些情况下，角回rTMS引起的干扰模式表明，该区域通常参与数字的空间表征。角回rTMS对数字线作业的影响具有特异性。RTMS在左半球或右半球的另一个顶区--边缘上回--传递时没有干扰效应。(C)2001年学术出版社。
To investigate the hemispheric organization of a language-independent spatial representation of number magnitude in the human brain we applied focal repetitive transcranial magnetic stimulation (rTMS) to the right or left angular gyrus while subjects performed a number comparison task with numbers between 31 and 99. Repetitive TMS over the angular gyrus disrupted performance of a visuospatial search task, and rTMS at the same site disrupted organization of the putative "number line." In some cases the pattern of disruption caused by angular gyrus rTMS suggested that this area normally mediates a spatial representation of number. The effect of angular gyrus rTMS on the number line task was specific. rTMS had no disruptive effect when delivered over another parietal region, the supramarginal gyrus, in either the left or the right hemisphere. (C) 2001 Academic Press.