miRNAs in endothelial cell signaling: the endomiRNAs.
miRNAs in endothelial cell signaling: the endomiRNAs.
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DOI:
10.1016/j.yexcr.2012.12.009
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发表时间:
2013-05-15
影响因子:
3.7
通讯作者:
Nicoli, S.
中科院分区:
文献类型:
--
作者:
Santoro, Massimo M.;Nicoli, S.
microRNAs (miRNAs) have a pivotal role during the formation and function of the cardiovascular system. More than 300 miRNAs have been currently found within the mammalian genome, however only few specific miRNAs, named endomiRNAs, showed conseved endothelial cell expression and function. In this review we present an overview of the currently know endo miRNAs, focusing on their genome localization, processing and target gene repression during vasculogenesis and angiogenesis.
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