Optimal control of blood glucose: the diabetic patient or the machine?
Optimal control of blood glucose: the diabetic patient or the machine?
复制标题
DOI：
10.1126/scitranslmed.3001083
复制
发表时间：
2010-04-14
影响因子：
17.1
通讯作者：
Edelman ER
中科院分区：
文献类型：
--
作者：
Brown L;Edelman ER
在这一期的《科学转化医学》中，El-Khatib等人描述了一种“闭环”双激素人工胰腺，旨在避免胰岛素依赖型糖尿病患者的低血糖发作。我们讨论了严格控制血糖治疗的益处和挑战，并询问这种和类似的技术突破是否可以解决糖尿病生物学中尚未解决的问题。
In this issue of Science Translational Medicine, El-Khatib et al. describe a “closed-loop” bi-hormonal artificial pancreas, designed to avert episodes of low blood sugar in patients with insulin-dependent diabetes. We discuss the benefits and challenges of therapy directed at tight control of blood glucose and ask whether this and similar technological breakthroughs can address as yet unanswered questions in the biology of diabetes.