Assessing Myocardial Disease Using T1ρ MRI
Assessing Myocardial Disease Using T1ρ MRI
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DOI：
10.1007/s12410-013-9248-7
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发表时间：
2014-02-01
影响因子：
0.9
通讯作者：
Witschey, Walter R. T.
中科院分区：
文献类型：
--
作者：
Han, Yuchi;Liimatainen, Timo;Witschey, Walter R. T.
磁共振成像（MRI）用于缺血性和非缺血性心肌病心肌疾病的无创评估有很大的兴趣。最近，有一个新的兴趣使用磁共振成像（MRI）技术利用自旋锁定射频（RF）脉冲，称为T-1 rho MRI。自旋锁定RF脉冲对一些核弛豫机制产生敏感性，如分子中水与酰胺、胺和羟基官能团之间的H-1交换；因此，有可能无创，不需要外源性造影剂，从病变心肌组织获得重要的分子信息。本文的目的是回顾和批判性地检查最近发表的与心肌疾病的T-1 rho MRI相关的文献。
There is great interest to use magnetic resonance imaging (MRI) for non-invasive assessment of myocardial disease in ischemic and non-ischemic cardiomyopathies. Recently, there has been a renewed interest to use a magnetic resonance imaging (MRI) technique utilizing spin locking radiofrequency (RF) pulses, called T-1 rho MRI. The spin locking RF pulse creates sensitivity to some mechanisms of nuclear relaxation such as H-1 exchange between water and amide, amine and hydroxyl functional groups in molecules; consequently, there is the potential to non-invasively, and without exogenous contrast agents, obtain important molecular information from diseased myocardial tissue. The purpose of this article is to review and critically examine the recent published literature in the field related to T-1 rho MRI ofmyocardial disease.