Selective attention to emotional stimuli in a verbal go/no-go task: an fMRI study

Selective attention to emotional stimuli in a verbal go/no-go task: an fMRI study
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DOI:
10.1097/00001756-200006050-00028
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发表时间:
2000-06-05
期刊:
影响因子:
1.7
通讯作者:
Dolan, RJ
Dolan, RJ
中科院分区:
医学4区
文献类型:
--
作者:
Elliott, R;Rubinsztein, JS;Dolan, RJ

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在焦虑和情感性障碍中,要求受试者注意词语的情绪属性的任务被用来研究情绪一致的信息加工偏差。在这项研究中,我们采用了一种情绪性的“去/不去”任务,利用功能磁共振成像来评估正常受试者关注词语情感属性的神经基质。研究发现,与以感知特征为基础的目标相比,以词汇意义为基础的目标的反应与额下回和前扣带背侧的反应相关。此外,选择情绪目标,无论是快乐还是悲伤,都与亚属扣带的反应增强有关,而快乐目标引起腹前扣带的神经反应增强。这些发现重申了内侧前额叶区域在正常情绪处理中的重要性。《神经病学报告》11:1739-1744 (C) 2000。
Tasks requiring subjects to attend emotional attributes of words have been used to study mood-congruent information processing biases in anxiety and affective disorders. In this study we adapted an emotional go/no-go task, for use with fMRI to assess the neural substrates of focusing on emotional attributes of words in normal subjects. The key findings were that responding to targets defined on the basis of meaning of words compared to targets defined on the basis of perceptual features was associated with response in inferior frontal gyrus and dorsal anterior cingulate. Further, selecting emotional targets, whether happy or sad, was associated with enhanced response in the subgenual cingulate, while happy targets elicited enhanced neural response in ventral anterior cingulate. These findings reaffirm the importance of medial prefrontal regions in normal emotional processing. NeuroReport 11:1739-1744 (C) 2000 Lippincott Williams & Wilkins.