Morphometrical malignancy grading is a valuable prognostic factor in invasive ductal breast cancer
Morphometrical malignancy grading is a valuable prognostic factor in invasive ductal breast cancer
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DOI：
10.1038/sj.bjc.6600617
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发表时间：
2002-11-18
影响因子：
8.8
通讯作者：
Collan, Y
中科院分区：
文献类型：
--
作者：
Kronqvist, P;Kuopio, T;Collan, Y
The aim of the present study is to augment the prognostic power of breast cancer grading by elaboration of quantitative histopathological methods. We focus on the recently introduced morphometrical grading system in which the three grading sub-features of the WHO grading system are evaluated with the help of computerised nuclear morphometry, and quantitative methods for assessing mitotic activity and tubular differentiation. The prognostic value of the morphometrical grading system is now confirmed in a material of 159 cases of invasive ductal breast cancer. In the current material the morphometrical grading system very efficiently predicted the prognosis of breast cancer by dividing the patients into favourable (grade I), intermediate (grade II), and unfavourable (grade III) outcome (P
