Neuromas and meningiomas: evaluation of early enhancement with dynamic MR imaging.
Neuromas and meningiomas: evaluation of early enhancement with dynamic MR imaging.
复制标题
神经瘤和脑膜瘤：用动态 MR 成像评估早期增强。
DOI：
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发表时间：
1992
期刊：
影响因子：
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通讯作者：
T. Kozuka
中科院分区：
文献类型：
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作者：
Keiko Fujii;Norihiko Fujita;N. Hirabuki;Tsutomu Hashimoto;Takashi Miura;T. Kozuka
目的
探讨动态磁共振成像在神经瘤和脑膜瘤分化中的作用。
方法
11 名神经瘤患者和 15 名脑膜瘤患者使用短 TE FLASH 序列和推注 Gd-DTPA 进行了动态对比增强 MR 成像。
结果
这些肿瘤在晚期信号增强增量方面没有显着差异，这对应于传统自旋回波成像中对比前和对比后图像之间的信号增强增量。然而，血管期的信号增强，即在动脉和静脉中识别出 Gd-DTPA 第一次通过的阶段，脑膜瘤中的信号增强大约是神经瘤中的四倍。差异具有统计学意义。此外，脑膜瘤比神经瘤具有更广泛的早期信号增强，反映了组织学多样性：两种血管母细胞脑膜瘤具有最高值，三种成纤维细胞脑膜瘤具有与神经瘤相当的最低值，而其他亚型脑膜瘤具有中间值。
结论
本研究结果表明，动态磁共振成像评估早期增强有助于神经瘤和脑膜瘤的鉴别，并可能有助于粗略预测脑膜瘤的病理亚型。
PURPOSE
To investigate the role of dynamic MR imaging in the differentiation of neuromas and meningiomas.
METHODS
Eleven patients with neuromas and 15 patients with meningiomas underwent dynamic contrast-enhanced MR imaging using a short TE FLASH sequence and a bolus injection of Gd-DTPA.
RESULTS
There was no significant difference between these tumors in the signal-enhancement increment at the late phase, which corresponds to the signal-enhancement increment between pre- and postcontrast images in conventional spin-echo imaging. However, the signal enhancement at the vascular phase, ie, the phase where the first passage of Gd-DTPA was recognized both in the arteries and veins, was approximately four times as high in meningiomas as in neuromas. The difference was statistically significant. Furthermore, meningiomas had a wider range of early signal enhancement than did neuromas, reflecting the histologic varieties: two angioblastic meningiomas had the highest values, and three fibroblastic the lowest values comparable with those of neuromas, while meningiomas with other subtypes had intermediate values.
CONCLUSIONS
The results of this study indicate that the evaluation of early enhancement with dynamic MR imaging is helpful in the differentiation of neuromas and meningiomas, and possibly in the crude prediction of pathologic subtypes of meningiomas.