Circadian Rhythms of Glycogen, Free Fatty Acids, and Triglycerides in Rat Heart and Diaphragm
Circadian Rhythms of Glycogen, Free Fatty Acids, and Triglycerides in Rat Heart and Diaphragm
复制标题
大鼠心脏和膈肌中糖原、游离脂肪酸和甘油三酯的昼夜节律
DOI：
10.3181/00379727-160-40458
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发表时间：
1979
影响因子：
--
通讯作者：
D. K. Meyer
中科院分区：
文献类型：
--
作者：
S. Garthwaite;Robert F. Morgan;D. K. Meyer
在大鼠心脏和膈肌糖原、FFA和TG中发现了与12：12光-暗周期一致的昼夜节律。虽然糖原和脂质的横膈膜节律几乎同时显示出峰值和最低值，但心脏基质节律的相位相差180°。这两种持续活动的肌肉类型显然对内源性底物的代谢和储存具有不同的控制机制。这些节律可能反映了两种肌肉中不同的代谢功能。心脏和膈肌代谢的昼夜节律研究为正常、无应激动物体内底物利用提供了一个有用的模型。
Summary Circadian rhythms entrainable to a 12:12 light-dark cycle have been found in rat heart and diaphragm glycogen, FFA and TG. While the diaphragm rhythms of glycogen and lipid exhibit nearly simultaneous peaks and nadirs, the heart substrate rhythms are 180° out of phase. The two continuously active muscle types apparently have different control mechanisms for the metabolism and storage of endogenous substrates. It is possible that these rhythms reflect different metabolic functions in the two muscles. Circadian studies of heart and diaphragm metabolism provide a useful model for in vivo substrate utilization in the normal, unstressed animal.